Abstract Inhibitory phosphatases. such as the inositol-5-phosphatase SHIP1 could potentially contribute to B-cell acute lymphoblastic leukemia (B-ALL) by raising the threshold for activation of the autoimmunity checkpoint. allowing malignant cells with strong oncogenic B-cell receptor signaling to escape negative selection. Here. https://www.parisnaturalfoodes.shop/product-category/graviola/