Objective: to investigate the impact of antirheumatic therapy carried out according to the treat-to-target (T2T) principle on the time course of changes in NT-proBNP levels in patients with early rheumatoid arthritis (RA) over an 18- month follow-up period. Subjects and methods. The investigation enrolled 74 patients. comprising 56 (74%) women (median age. https://parisnaturalfoodes.shop/product-category/echinacea-toothpaste/