HIV-1 cure strategy by means of proviral knock-out using CRISPR-Cas9 has been hampered by the emergence of viral resistance against the targeting guide RNA (gRNA). Here. we proposed multiple. concentrated gRNA attacks against HIV-1 regulatory genes to block viral escape. https://www.chiggate.com/us-topo-7-5-minute-map-for-cucharas-reservoir-co-for-sale/