Toll-like receptors (TLRs) are highly-conserved pattern recognition receptors that mediate innate immune responses to invading pathogens and endogenous danger signals released from damaged and dying cells. Activation of TLRs trigger downstream signaling cascades. that culminate in the activation of interferon regulatory factors (IRFs). which subsequently leads to type I interferon (IF... https://www.pomyslnaszycie.com/